PCSK9, Mouse (HEK293, His)
HY-P71189A
Protein IDQ80W65
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NamePCSK9, Mouse (HEK293, His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity98.0
- Gene ID100102
- Target namePcsk9
- Target descriptionproprotein convertase subtilisin/kexin type 9
- Target synonymsFH3, HCHOLA3, Narc1, PC9, proprotein convertase subtilisin/kexin type 9, NARC-1, convertase subtilisin, neural apoptosis regulated convertase 1, proprotein convertase 9, proprotein convertase PC9, subtilisin/kexin-like protease PC9
- Protein IDQ80W65
- Protein NameProprotein convertase subtilisin/kexin type 9
- Scientific DescriptionThe PCSK9 protein regulates cholesterol levels by degrading LDLR, VLDLR, LRP1/APOER, and LRP8/APOER2 receptors. It promotes LDLR degradation, inhibits recycling, induces ubiquitination, and affects APOB degradation. Additionally, PCSK9 influences BACE1 intermediates, ENaC surface expression, and neuronal apoptosis by modulating LRP8/APOER2 levels and anti-apoptotic signaling pathways. PCSK9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PCSK9 protein, expressed by HEK293, with C-6*His labeled tag.
- Storage Instruction-20°C
- UNSPSC41116100