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PCSK9, Mouse (HEK293, His)

HY-P71189A
MedChem Express
Protein IDQ80W65
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PCSK9, Mouse (HEK293, His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Gene ID100102
  • Target name
    Pcsk9
  • Target description
    proprotein convertase subtilisin/kexin type 9
  • Target synonyms
    AI415265; AI747682; convertase subtilisin; FH3; HCHOLA3; Na; Narc1; NARC-1; neural apoptosis regulated convertase 1; PC9; proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; subtilisin/kexin-like protease PC9
  • Protein IDQ80W65
  • Protein Name
    Proprotein convertase subtilisin/kexin type 9
  • Scientific Description
    The PCSK9 protein regulates cholesterol levels by degrading LDLR, VLDLR, LRP1/APOER, and LRP8/APOER2 receptors. It promotes LDLR degradation, inhibits recycling, induces ubiquitination, and affects APOB degradation. Additionally, PCSK9 influences BACE1 intermediates, ENaC surface expression, and neuronal apoptosis by modulating LRP8/APOER2 levels and anti-apoptotic signaling pathways. PCSK9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PCSK9 protein, expressed by HEK293, with C-6*His labeled tag.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100