Bio-Connect

PCSK9, Rat (HEK293, His)

HY-P73340
MedChem Express
Protein IDP59996
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PCSK9, Rat (HEK293, His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    95.0
  • Gene ID298296
  • Target name
    Pcsk9
  • Target description
    proprotein convertase subtilisin/kexin type 9
  • Target synonyms
    Narc1; NARC-1; neural apoptosis-regulated convertase 1; PC9; proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; subtilisin/kexin-like protease PC9
  • Protein IDP59996
  • Protein Name
    Proprotein convertase subtilisin/kexin type 9
  • Scientific Description
    The PCSK9 protein regulates cholesterol levels by interacting with LDLR, VLDLR, LRP1/APOER, and LRP8/APOER2. It promotes their degradation and inhibits their recycling, leading to enhanced LDLR degradation. PCSK9 also affects APOB degradation, BACE1 intermediates, ENaC surface expression, and neuronal apoptosis via LRP8/APOER2. PCSK9 Protein, Rat (HEK293, His) is the recombinant rat-derived PCSK9 protein, expressed by HEK293 , with C-6*His labeled tag.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100