PD 128042 [114289-47-3]

MedChem Express

PD 128042 [114289-47-3]

10

114289-47-3

Research Use Only

99.97

C23H39NO4

393.56

PD 128042 (CI 976) is a potent, orally active, and selective inhibitor of ACAT (acyl coenzyme A:cholesterol acyltransferase) with an IC50s of 73 nM. PD 128042 is also a potent LPAT (lysophospholipid acyltransferase) inhibitor. PD 128042 inhibits Golgi-associated LPAT activity (IC50=15 microM). PD 128042 inhibits multiple membrane trafficking steps, including ones found in the endocytic and secretory pathway[1][2][3].

CCCCCCCCCCC(C)(C)C(NC1=C(C=C(OC)C=C1OC)OC)=O

-20°C,2°C to 8°C

12352200