PD 136450 [139067-52-0]

MedChem Express

PD 136450 [139067-52-0]

5

139067-52-0

Research Use Only

C35H40N4O6

612.72

PD 136450 (CAM 1189) is an antagonist for cholecystokinin 2 (CCK2). PD 136450 exhibits anti-secretory, anxiolytic and anti-ulcer activities, inhibits gastric acid secretion (IC50=1 mg/kg), and ameliorates the haemorrhagic lesions (IC50=4.7 mg/kg) in rats[1].

O=C(/C=C/C(N[C@@H](CNC([C@@](C)(CC1=CNC2=C1C=CC=C2)NC(OC3C4CC(CC3C5)CC5C4)=O)=O)C6=CC=CC=C6)=O)O

12352200