PD-166793

MedChem Express

PD-166793 [199850-67-4]

10

199850-67-4

Research Use Only

99.45

C17H18BrNO4S

412.30

PD-166793 is a potent, selective, orally active and wide-broad spectrum inhibitor of MMP , exhibiting nanomolar potency against MMP-2 , MMP-3 and MMP-13 ( IC 50 =4, 7, and 8 nM, respectively) and micromolar potency vs MMP-1 , -7 and -9 ( IC 50 =6.0, 7.2, and 7.9 microM, respectively). PD-166793 can attenuate left ventricular remodeling and dysfunction in a rat model of progressive heart failure [1] [2] [3] .

CC(C)[C@@H](C(O)=O)NS(=O)(C1=CC=C(C2=CC=C(Br)C=C2)C=C1)=O

-20°C,2°C to 8°C

12352200