PD 168568

Biorbyt

PD 168568

10

210688-56-5

Research Use Only

98.00%

C22H27N3O

349.47

PD 168568, an orally active and potent dopamine receptor D4 (DRD4) antagonist featuring an isoindolinone structure, demonstrates selective affinity for the D4 receptor over D2 and D3 receptors, with K i values of 8.8, 1842, and 2682 nM, respectively. This compound is utilized in glioblastoma (GBM) research.

C(CN1CCN(CC1)C2=CC(C)=C(C)C=C2)C3C=4C(C(=O)N3)=CC=CC4

-20°C

12352200