PD 168568 (dihydrochloride)

MedChem Express

PD 168568 (dihydrochloride) [1782532-06-2]

10

1782532-06-2

C22H29Cl2N3O

422.39

PD 168568 dihydrochloride is a orally active and potent dopamine receptor D 4 (DRD 4 ) antagonist. PD 168568 dihydrochloride contains an isoindolinone and is selective for the D 4 receptor versus D 2 and D 3 , with K i values of 8.8, 1842, and 2682 nM, respectively. PD 168568 dihydrochloride can be used for glioblastoma (GBM) research [1] [2] .

O=C1NC(CCN2CCN(C3=CC=C(C)C(C)=C3)CC2)C4=C1C=CC=C4.[H]Cl.[H]Cl

12352200