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ProductsBack/PD-173955 [260415-63-2]
Chemical Structure
Chemical Structure
Chemical Structure

PD-173955 [260415-63-2]

SYN-1061
SYNkinase
CAS Number260415-63-2
Product group Chemicals
Estimated Purity>95%
Molecular Weight443.4
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Overview

  • Supplier
    SYNkinase
  • Product Name
    PD-173955 [260415-63-2]
  • Delivery Days Customer
    10
  • CAS Number
    260415-63-2
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C21H16Cl2N4OS
  • Molecular Weight
    443.4
  • Scientific Description
    Chemical. CAS: 260415-63-2. Formula: C21H16Cl2N4OS. MW: 443.4. PD173955 is an ATP-competitive, dual Src/Bcr-Abl kinase inhibitor. It is a potent inhibitor of Bcr-Abl with an IC(50) of 1-2nM in kinase inhibition assays. In cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 also inhibits Src kinase activity in vitro with an IC(50) of 22nM and could represent a novel class of anti-mitotic drug. - PD173955 is an ATP-competitive, dual Src/Bcr-Abl kinase inhibitor. It is a potent inhibitor of Bcr-Abl with an IC(50) of 1-2nM in kinase inhibition assays. In cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 also inhibits Src kinase activity in vitro with an IC(50) of 22nM and could represent a novel class of anti-mitotic drug.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    51202000