PD 184,352

Bioss Antibodies

PD 184,352 [212631-79-3]

16

Research Use Only

>98%

MEK (MAPKK) inhibitor [5]. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo) [1, 2]. Suppresses activation of MAPK but does not block its activity [3]. Antiproliferative [4]. Causes cell-cycle arrest in G1 phase [4]. Tumor suppressor [1, 5]. Apoptosis inducer [6].

-20°C

51202000