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ProductsBack/PD 184,352 [212631-79-3]
Chemical Structure
Chemical Structure
Chemical Structure

PD 184,352 [212631-79-3]

Research Use Only
AG-CR1-0029
AdipoGen Life Sciences
CAS Number212631-79-3
DownloadMSDS
Product group Chemicals
Estimated Purity>98%
Molecular Weight478.7
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    PD 184,352
  • Delivery Days Customer
    10
  • CAS Number
    212631-79-3
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Warning
  • Molecular Formula
    C17H14ClF2IN2O2
  • Molecular Weight
    478.7
  • Scientific Description
    Chemical. CAS: 212631-79-3. Formula: C17H14ClF2IN2O2. MW: 478.7. MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer. - MEK (MAPKK) inhibitor [5]. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo) [1, 2]. Suppresses activation of MAPK but does not block its activity [3]. Antiproliferative [4]. Causes cell-cycle arrest in G1 phase [4]. Tumor suppressor [1, 5]. Apoptosis inducer [6].
  • SMILES
    FC1=C(F)C(NC2=CC=C(I)C=C2Cl)=C(C=C1)C(=O)NOCC1CC1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200