PD0166285

MedChem Express

PD0166285 [185039-89-8]

10

185039-89-8

Research Use Only

99.46

C26H27Cl2N5O2

512.43

PD0166285, a substrate of P-gp, is a WEE1 inhibitor and a weak Myt1 inhibitor with IC 50 values of 24 and 72 nM, respectively. PD0166285 exhibits an IC 50 of 3.433 microM for Chk1 [1] .

O=C1N(C)C2=NC(NC3=CC=C(OCCN(CC)CC)C=C3)=NC=C2C=C1C4=C(Cl)C=CC=C4Cl

-20°C,2°C to 8°C

12352200