PD07

MedChem Express

PD07

14

Research Use Only

C23H21ClN2O4

424.88

PD07 is an orally active AChE inhibitor (IC50: 0.29 microM for hAChE). PD07 also inhibits ChEs, BACE1 (IC50: 13.42 microM), and Abeta1-42 aggregation in in vitro. PD07 is an antioxidant, and shows DPPH inhibitory activity (IC50: 26.46 microM). PD07 improves memory and cognition in Scopolamine (HY-N0296)-induced amnesia rats. PD07 can be used for research of Alzheimers disease[1].

ClC1=CC=C(C(N2CCN(C(/C=C/C=C/C3=CC(OCO4)=C4C=C3)=O)CC2)=O)C=C1

12131703