PD1-PDL1-IN 2

Biorbyt

PD1-PDL1-IN 2

10

Research Use Only

98.00%

C37H41ClN4O7S

721.26

PD1-PDL1-IN 2 (ZE132) is a potent, selective inhibitor of PD-1/PD-L1, exhibiting significant anti-tumor activity in vivo. It enhances cytotoxic T-cell tumor infiltration and stimulates IL-2 expression, while also strongly inhibiting TGF-beta [1] mRNA expression, showcasing its comprehensive immunotherapeutic potential.

CC1=C(C=2C=C3C(=CC2)OCCO3)C=CC=C1COC4=CC(OCC=5C=C(C#N)C=NC5)=C(CN(CCCN(C)C)CCS(=O)(=O)O)C=C4Cl

-20°C

12352200