PD184161 [212631-67-9]

MedChem Express

PD184161 [212631-67-9]

10

212631-67-9

Research Use Only

98.08

C17H13BrClF2IN2O2

557.56

PD184161 is an orally active MEK inhibitor. PD184161 inhibits MEK activity (IC50=10-100 nM) in a time- and concentration-dependent manner. PD184161 inhibits cell proliferation and induces apoptosis. PD184161 produces depressive-like behavior[1][2].

O=C(NOCC1CC1)C2=CC(Br)=C(F)C(F)=C2NC(C(Cl)=C3)=CC=C3I

2°C to 8°C

12352200