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Gel: 10%SDS-PAGE, Lysate: 60 ug, Lane: K562 cells, Primary antibody: CSB-PA442649(PDCD4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
Gel: 10%SDS-PAGE, Lysate: 60 ug, Lane: K562 cells, Primary antibody: CSB-PA442649(PDCD4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
Gel: 10%SDS-PAGE, Lysate: 60 ug, Lane: K562 cells, Primary antibody: CSB-PA442649(PDCD4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes

PDCD4 Antibody

CSB-PA442649
Cusabio
TargetPDCD4
Product group Antibodies
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Overview

  • Supplier
    Cusabio
  • Product Name
    PDCD4 Antibody
  • Delivery Days Customer
    20
  • Formulation
    Liquid
  • Gene ID27250
  • Target name
    PDCD4
  • Target description
    programmed cell death 4
  • Target synonyms
    H731; neoplastic transformation inhibitor protein; nuclear antigen H731; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; protein 197/15a
  • Protein IDQ53EL6
  • Protein Name
    Programmed cell death protein 4
  • Scientific Description
    This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation.
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203