Gel: 10%SDS-PAGE, Lysate: 60 ug, Lane: K562 cells, Primary antibody: CSB-PA442649(PDCD4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
Gel: 10%SDS-PAGE, Lysate: 60 ug, Lane: K562 cells, Primary antibody: CSB-PA442649(PDCD4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
PDCD4 Antibody
CSB-PA442649
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetPDCD4
Overview
- SupplierCusabio
- Product NamePDCD4 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID27250
- Target namePDCD4
- Target descriptionprogrammed cell death 4
- Target synonymsH731; neoplastic transformation inhibitor protein; nuclear antigen H731; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; protein 197/15a
- HostRabbit
- IsotypeIgG
- Protein IDQ53EL6
- Protein NameProgrammed cell death protein 4
- Scientific DescriptionThis gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203