PDCD6 Polyclonal Antibody

Elabscience

PDCD6 Polyclonal Antibody

12

Western Blot, ImmunoHistoChemistry

ELISA WB IHC

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

PDCD6

programmed cell death 6

ALG-2, ALG2, PEF1B, programmed cell death protein 6, apoptosis-linked gene 2 protein homolog, probable calcium-binding protein ALG-2

Rabbit

IgG

Programmed cell death protein 6

This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

-20°C

41116161