PDE12-IN-1 [2259620-80-7]

MedChem Express

PDE12-IN-1 [2259620-80-7]

5

2259620-80-7

Research Use Only

98.85

C31H27BrFN5O3

616.48

PDE12-IN-1 is a potent and selective PDE12 inhibitor with a pIC50 value for enzyme inhibition of 9.1. PDE12-IN-1 increases 2,5-linked adenylate polymers (2-5A) levels, and the pEC50 value is 7.7. PDE12-IN-1 shows antiviral activity[1].

N#CC1=CC2=C(C=C1)C(C3=NC4=CC(Br)=C(C(N5[C@H](CO)[C@@H](C6=CC=C(F)C=C6)OCC5)=O)C=C4N3C)=CN2CC

2°C to 8°C

12352200