PDE1A antibody

GeneTex

PDE1A antibody

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.74 mg/ml

Unconjugated

PDE1A

phosphodiesterase 1A

61 kDa Cam-PDE; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; CAM-PDE 1A; CAM-PDE-1A; HCAM1; HCAM-1; HSPDE1A; phosphodiesterase 1A, calmodulin-dependent

Rabbit

IgG

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM]

-20°C or -80°C,2°C to 8°C

12352203