PDE3A, Human (sf9, His-GST)

MedChem Express

PDE3A, Human (sf9, His-GST)

10

Research Use Only

90.00

PDE3A

phosphodiesterase 3A

CGI-PDE, CGI-PDE A, CGI-PDE-A, HTNB, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A, cAMP phosphodiesterase, myocardial cGMP-inhibited, cGMP-inhibited 3',5'-cyclic phosphodiesterase A, cGMP-inhibited cAMP phosphodiesterase, cyclic GMP-inhibited phosphodiesterase A, phosphodiesterase 3A, cGMP-inhibited

cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

PDE3A protein, a cyclic nucleotide phosphodiesterase, targets cAMP, cGMP, and cUMP, crucial in diverse physiological processes. In an E2/17beta-estradiol-induced pro-apoptotic pathway, E2 stabilizes the PDE3A/SLFN12 complex, leading to SLFN12 dephosphorylation and activating its pro-apoptotic ribonuclease activity. This pathway is implicated in tissues with high E2 concentrations, potentially contributing to processes like placenta remodeling. PDE3A Protein, Human (sf9, His-GST) is the recombinant human-derived PDE3A protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

-80°C

41116100

Human