PDE4A antibody

GeneTex

PDE4A antibody

9

This antibody labels all known PDE4A variants including PDE4A1 (66 kDa), PDE4A5 (109 kDa), PDE4A8 (106 kDa), AND PDE4Ax (10 kDa) and a 76 kDa testis specific A variant.

WB: 1:1000-1:2500. ICC/IF: 1:100-1:400. IHC-P: 1:100-1:400. IHC-Fr: 1:100-1:400. IP: 1:250. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

PDE4A

phosphodiesterase 4A

cAMP-specific 3',5'-cyclic phosphodiesterase 4A; DPDE2; PDE4; PDE46; phosphodiesterase 4A, cAMP-specific (dunce; phosphodiesterase E2 dunce homolog, Drosophila; phosphodiesterase isozyme 4

Rabbit

IgG

cAMP-specific 3',5'-cyclic phosphodiesterase 4A

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Human, Mammals, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203