PDE8B antibody

GeneTex

PDE8B antibody

9

WB: 1:500-1:2000. ICC/IF: 1:200. IP: 1:250. ELISA: 1:10000. IHC: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

PDE8B

phosphodiesterase 8B

ADSD, PPNAD3, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, 3',5' cyclic nucleotide phosphodiesterase 8B, cell proliferation-inducing gene 22 protein

Rabbit

IgG

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

-20°C or -80°C,2°C to 8°C

12352203