Western Blot Positive WB detected in: A549 whole cell lysate All lanes: PDE9A antibody at 3.9microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 69, 62, 55, 63, 58, 46, 59, 51, 45, 54, 65, 66, 57 kDa Observed band size: 69 kDa
Western Blot Positive WB detected in: A549 whole cell lysate All lanes: PDE9A antibody at 3.9microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 69, 62, 55, 63, 58, 46, 59, 51, 45, 54, 65, 66, 57 kDa Observed band size: 69 kDa
PDE9A Antibody
CSB-PA527985LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPDE9A
Overview
- SupplierCusabio
- Product NamePDE9A Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5152
- Target namePDE9A
- Target descriptionphosphodiesterase 9A
- Target synonymsCGMP-specific 3',5'-cyclic phosphodiesterase type 9; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; HSPDE9A2; phosphodiesterase PDE9A21
- HostRabbit
- IsotypeIgG
- Protein IDO76083
- Protein NameHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
- Scientific DescriptionSpecifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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