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PDGFRalpha kinase inhibitor 2 [404844-11-7]

HY-W143698
MedChem Express
CAS Number404844-11-7
Product group Chemicals
Estimated Purity98.95
Molecular Weight429.90
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PDGFRalpha kinase inhibitor 2 [404844-11-7]
  • Delivery Days Customer
    5
  • CAS Number
    404844-11-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.95
  • Molecular Formula
    C24H20ClN5O
  • Molecular Weight
    429.90
  • Scientific Description
    PDGFRalpha kinase inhibitor 2 (compound 1), an Imatinib (HY-15463) analogue, is a covalent and irreversible kinase inhibitor with IC50s of 6.95 microM, 2.45 microM, 1.39 microM for ABL1 wt, KIT wt, PDGFRR wt[1].
  • SMILES
    O=C(C1=CC=C(CCl)C=C1)NC2=CC=C(C)C(NC3=NC(C4=CN=CC=C4)=CC=N3)=C2
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200