PDHK-IN-4

MedChem Express

PDHK-IN-4

10

Research Use Only

C24H25N5O3

431.49

PDHK-IN-4 (Compound 30) is a potent inhibitor of PDHK with IC50s of 0.0051 and 0.0122 microM for PDHK2 and PDHK4, repectively. Pyruvate dehydrogenase kinases (PDHKs) are fascinating agent targets for numerous diseases, including diabetes and cancers. PDHK-IN-4 has the potential for the research of cancer diseases[1].

O=C(C1=CC=C([C@@H]2CN(C3=C4C(NC5=C4C=CC=C5C6CC6)=NC(C)=N3)[C@H](CO)C2)N1)O

12131703