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PDK1-IN-2 [1643958-85-3]

HY-117809
MedChem Express
CAS Number1643958-85-3
Product group Chemicals
Estimated Purity98.90
Molecular Weight380.89
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PDK1-IN-2 [1643958-85-3]
  • Delivery Days Customer
    5
  • CAS Number
    1643958-85-3
  • Certification
    Research Use Only
  • Estimated Purity
    98.90
  • Molecular Formula
    C15H9ClN2O2S3
  • Molecular Weight
    380.89
  • Scientific Description
    PDK1-IN-2 is a small molecule inhibitor of 3-phosphoinositol-dependent protein kinase-1 (PDK1). PDK1-IN-2 inhibits the binding of PDK1 to its substrate by competitively binding to the PIF pocket of PDK1, thereby inhibiting the kinase activity and downstream signaling of PDK1. PDK1-IN-2 can be used for cell survival and proliferation in cancer[1].
  • SMILES
    O=S(NC1=NC2=C(S1)C=C(Cl)C=C2)(C3=CSC4=C3C=CC=C4)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200