PDZK1 Antibody

Cusabio

PDZK1 Antibody

20

ELISA

Research Use Only

Polyclonal

Unconjugated

PDZK1

PDZ domain containing 1

CAP70, CLAMP, NHERF-3, NHERF3, PDZD1, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, CFTR-associated protein of 70 kDa, Na(+)/H(+) exchange regulatory cofactor 3, PDZ-containing kidney protein 1, na/Pi cotransporter C-terminal-associated protein 1, naPi-Cap1, sodium-hydrogen exchanger regulatory factor 3

Rabbit

IgG

Na(+)/H(+) exchange regulatory cofactor NHE-RF3

A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function

Human

-20°C or -80°C

41116161