PE Anti-Mouse CD107a Antibody

Reddot Biotech

PE Anti-Mouse CD107a Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

1D4B

RPE

Lamp1

lysosomal-associated membrane protein 1

CD107a, LGP-120, LGP-A, Lamp-1, P2B, Perk, lysosome-associated membrane glycoprotein 1, 120 kDa lysosomal membrane glycoprotein, CD107 antigen-like family member A, LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B), Lamp I, lysosomal membrane glycoprotein 1, lysosomal membrane glycoprotein A, lysosome-associated membrane protein 1

Rat

IgG2a

The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa.??It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

2°C to 8°C

12352203