PE/Cyanine7 Anti-Rat CD44H Antibody

Reddot Biotech

PE/Cyanine7 Anti-Rat CD44H Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

OX-49

Double Conjugated

Cd44

CD44 antigen

HERMES, Ly-24, Pgp-1, CD44 antigen, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, PGP-I, extracellular matrix receptor III, hermes antigen, hyaluronate receptor, lymphocyte antigen 24, phagocytic glycoprotein 1, phagocytic glycoprotein I

Mouse

IgG2a

CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

2°C to 8°C

12352203