PEG10 Antibody

Cusabio

PEG10 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

PEG10

paternally expressed 10

EDR, HB-1, MEF3L, Mar2, Mart2, RGAG3, RTL2, SIRH1, retrotransposon-derived protein PEG10, MEF3 like 1, Sushi-Ichi retrotransposon homolog 1, embryonal carcinoma differentiation regulated, mammalian retrotransposon-derived 2, mammalian retrotransposon-derived protein 2, myelin expression factor 3-like protein 1, paternally expressed gene 10 protein, retrotransposon Gag like 2, retrotransposon gag domain-containing protein 3, retrotransposon-derived gag-like polyprotein, ty3/Gypsy-like protein

Rabbit

IgG

Retrotransposon-derived protein PEG10

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.

Human

-20°C or -80°C

41116161