Peldesine [133432-71-0]

MedChem Express

Peldesine [133432-71-0]

10

133432-71-0

Research Use Only

98.06

C12H11N5O

241.25

Peldesine (BCX 34) is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research[1][2][3][4].

O=C1C(NC=C2CC3=CC=CN=C3)=C2N=C(N)N1

-20°C,2°C to 8°C

12352200