Pelitrexol [446022-33-9]
HY-14530
CAS Number446022-33-9
Product group Chemicals
Estimated Purity98.94
Molecular Weight463.51
Overview
- SupplierMedChem Express
- Product NamePelitrexol [446022-33-9]
- Delivery Days Customer9
- CAS Number446022-33-9
- CertificationResearch Use Only
- Estimated Purity98.94
- Molecular FormulaC20H25N5O6S
- Molecular Weight463.51
- Scientific DescriptionPelitrexol (AG 2037) is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), a purine biosynthetic enzyme. Pelitrexol also inhibits mTORC1 by reducing GTP-bound Rheb level, a mTORC1 obligate activator. Pelitrexol shows robust tumor growth suppression in mice[1].
- SMILESO=C(O)CC[C@@H](C(O)=O)NC(C1=CC(C)=C(CC[C@H](CN2)CC3=C2N=C(N)NC3=O)S1)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![Pelitrexol [446022-33-9]](https://www.targetmol.com/group3/M00/35/FD/CgoaEWayM9iEATdFAAAAAJG5cn8098.png)