Bio-Connect

Pelitrexol [446022-33-9]

HY-14530
MedChem Express
CAS Number446022-33-9
Product group Chemicals
Estimated Purity98.94
Molecular Weight463.51
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Pelitrexol [446022-33-9]
  • Delivery Days Customer
    9
  • CAS Number
    446022-33-9
  • Certification
    Research Use Only
  • Estimated Purity
    98.94
  • Molecular Formula
    C20H25N5O6S
  • Molecular Weight
    463.51
  • Scientific Description
    Pelitrexol (AG 2037) is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), a purine biosynthetic enzyme. Pelitrexol also inhibits mTORC1 by reducing GTP-bound Rheb level, a mTORC1 obligate activator. Pelitrexol shows robust tumor growth suppression in mice[1].
  • SMILES
    O=C(O)CC[C@@H](C(O)=O)NC(C1=CC(C)=C(CC[C@H](CN2)CC3=C2N=C(N)NC3=O)S1)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200