Pemetrexed

MedChem Express

Pemetrexed [137281-23-3]

10

137281-23-3

Research Use Only

99.95

C20H21N5O6

427.41

Pemetrexed (LY231514) is an antifolate , the K i values of the pentaglutamate of Pemetrexed (LY231514) are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase ( TS ), dihydrofolate reductase ( DHFR ), and glycinamide ribonucleotide formyltransferase ( GARFT ), respectively [1] .

O=C1NC(N)=NC2=C1C(CCC3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3)=CN2

-20°C,2°C to 8°C

12352200