Pemetrexed (disodium)-13C5

MedChem Express

Pemetrexed (disodium)-13C5

999

Research Use Only

C15 13C5H19N5Na2O6

476.34

Pemetrexed disodium-13C5 (LY231514 disodium-13C5) is the 13C-labeled Pemetrexed disodium (HY-10820A). Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively[1].

O=C1N=C(NC2=C1C(CCC3=CC=C(C=C3)C(N[13C@@H]([13CH2][13CH2][13C](O[Na])=O)[13C](O[Na])=O)=O)=CN2)N

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