Pemigatinib [1513857-77-6]

MedChem Express

Pemigatinib [1513857-77-6]

10

1513857-77-6

Research Use Only

99.84

C24H27F2N5O4

487.50

Pemigatinib (INCB054828) is an orally active, selective FGFR inhibitor with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma[1][2].

CCN(C(N(C(C(F)=C(OC)C=C1OC)=C1F)C2)=O)C(C2=CN3)=C4C3=NC(CN5CCOCC5)=C4

-20°C,2°C to 8°C

12352200