Penciclovir [39809-25-1]

TargetMol Chemicals

Penciclovir [39809-25-1]

4

39809-25-1

Chemical

Research Use Only

Penciclovir

99.10%

C10H15N5O3

253.26

Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the active metabolite, penciclovir triphosphate, which competitively inhibits viral HSV polymerase by blocking deoxyguanosine triphosphate substrate binding. As a result, herpes viral DNA synthesis and replication are selectively inhibited.

3 years

C(CC(CO)CO)N1C2=C(N=C1)C(=O)N=C(N)N2

-20°C

12352200