Penfluridol

MedChem Express

Penfluridol [26864-56-2]

5

26864-56-2

99.93

C28H27ClF5NO

523.97

Penfluridol (R-16341) is a potent, long-acting, first-generation, oral diphenylbutylpiperidine antipsychotic agent by targeting D2-like dopamine receptor . Penfluridol effectively inhibits TNFalpha-induced NF-kappaB activation and alleviates the severity of arthritis and colitis in vivo. Penfluridol is a Ca 2+ -calmodulin inhibitor. Penfluridol induces apoptosis and autophagy . Penfluridol is used for chronic schizophrenia, acute psychosis, Tourette syndrome and autoimmune diseases. Penfluridol inhibites the growth of E. faecalis planktonic cells with the MIC of 7.81 microg/ml [1] [2] [3] [4] .

OC1(C2=CC=C(Cl)C(C(F)(F)F)=C2)CCN(CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC1

-20°C,2°C to 8°C

12352200