Pentachloropseudilin

MedChem Express

Pentachloropseudilin [69640-38-6]

10

69640-38-6

Research Use Only

98.88

C10H4Cl5NO

331.41

Pentachloropseudilin (Antibiotic A 15104 Y; PClP) is a reversible and allosteric potent inhibitor of Myo1s (class 1 myosins) with IC 50 s range from 1 to 5 microM for mammalian class-1 myosins and greater than 90 microM for class-2 and class-5 myosins. Pentachloropseudilin is a potent inhibitor of transforming growth factor-beta (TGF-beta) -stimulated signaling, with an IC 50 of 0.1 to 0.2 microM for TGF-beta [1] [2] .

OC1=C(C2=C(Cl)C(Cl)=C(Cl)N2)C=C(Cl)C=C1Cl

-20°C

12352200