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The data was published in the journal PLoS One in 2015. PMID: 25774777
The data was published in the journal PLoS One in 2015. PMID: 25774777
The data was published in the journal PLoS One in 2015. PMID: 25774777

Pentraxin 3 antibody, N-term

Research Use Only
GTX45054
GeneTex
ApplicationsElectron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPTX3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Pentraxin 3 antibody, N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 0.2-2.5 ug/ml. IHC-P: 2-10 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Electron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5-1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID5806
  • Target name
    PTX3
  • Target description
    pentraxin 3
  • Target synonyms
    long pentraxin 3; pentraxin-related protein PTX3; TNF alpha-induced protein 5; TNFAIP5; TSG-14; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP26022
  • Protein Name
    Pentraxin-related protein PTX3
  • Scientific Description
    This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Immunization with Pentraxin3 prevents transition from subclinical to clinical lupus nephritis in lupus-prone mice: Insights from renal ultrastructural findings. Gatto M et al., 2020 Jul, J Autoimmun
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  • The long pentraxin PTX3 promotes fibrocyte differentiation. Pilling D et al., 2015, PLoS One
    Read more