PerCP Anti-Mouse CD45R/B220 Antibody

Reddot Biotech

PerCP Anti-Mouse CD45R/B220 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

RA3.3A 1/6.1

PerCP

PTPRC

protein tyrosine phosphatase receptor type C

B220, CD45, CD45R, GP180, IMD105, L-CA, LCA, LY5, T200, receptor-type tyrosine-protein phosphatase C, CD45 antigen, T200 glycoprotein, T200 leukocyte common antigen, glycoprotein 180, protein tyrosine phosphatase, receptor type, c polypeptide

Rat

IgM

CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. - This is a PerCP Anti-Mouse CD45R/B220 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Mouse

2°C to 8°C

41116161