PerCP/Cyanine5.5 Anti-Human CD22 Antibody
RD20673F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetCD22
Overview
- SupplierReddot Biotech
- Product NamePerCP/Cyanine5.5 Anti-Human CD22 Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDBU59
- ConjugateDouble Conjugated
- Gene ID933
- Target nameCD22
- Target descriptionCD22 molecule
- Target synonymsB-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigen; sialic acid-binding Ig-like lectin 2; SIGLEC2; SIGLEC-2; T-cell surface antigen Leu-14
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase COe≥1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203