Perforin antibody

GeneTex

Perforin antibody

9

WB: Use at a dilution of 1/1000. MW ~70kD Optimal dilutions/concentrations should be determined by the end user.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Prf1

perforin 1

Cyta; cytolysin; lymphocyte pore-forming protein; P1; perforin 1 (pore forming protein); perforin-1; RATCYTA

Rabbit

IgG

Perforin (pore-forming protein) is originally cloned from mouse cytotoxic T-lymphocyte(CTL) (ref 1,2). It is a 555-amino acid protein with a 21-amino acid signal peptide. Perforin is a cytolytic mediator produced by killer lymphocytes, and is stored in and released by cytoplasmic granules. Perforin is involved in the killing mediated by CTL, which represents an important mechanism in the immune defense against tumors and virus infections (ref 3,4).

Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203