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Periostin antibody

GTX100602
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPOSTN
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Overview

  • Supplier
    GeneTex
  • Product Name
    Periostin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.29 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10631
  • Target name
    POSTN
  • Target description
    periostin
  • Target synonyms
    OSF-2, OSF2, PDLPOSTN, PN, periostin, osteoblast specific factor 2 (fasciclin I-like), periodontal ligament-specific periostin, periostin, osteoblast specific factor
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15063
  • Protein Name
    Periostin
  • Scientific Description
    Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Hosiriluck N, Kashio H, Takada A, et al. The profiling and analysis of gene expression in human periodontal ligament tissue and fibroblasts. Clin Exp Dent Res. 2022,8(3):658-672. doi: 10.1002/cre2.533
    Read this paper
  • Chen YT, Jhao PY, Hung CT, et al. Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts. J Clin Invest. 2021,131(5):pii: 143645. doi: 10.1172/JCI143645.
    Read this paper
  • Lee TH, Yeh CF, Lee YT, et al. Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization. Nat Commun. 2020,11(1):4254. doi: 10.1038/s41467-020-18047-x
    Read this paper
  • Song X, Yu W, Guo F. Pirfenidone suppresses bleomycin-induced pulmonary fibrosis and periostin expression in rats. Exp Ther Med. 2018,16(3):1800-1806. doi: 10.3892/etm.2018.6378
    Read this paper
  • Gueugneau M, d'Hose D, Barbé C, et al. Increased Serpina3n release into circulation during glucocorticoid-mediated muscle atrophy. J Cachexia Sarcopenia Muscle. 2018,9(5):929-946. doi: 10.1002/jcsm.12315
    Read this paper
  • Shih YC, Chen CL, Zhang Y, et al. Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation. Circ Res. 2018,122(8):1052-1068. doi: 10.1161/CIRCRESAHA.117.312130
    Read this paper
  • Nakazawa Y, Taniyama Y, Sanada F, et al. Periostin blockade overcomes chemoresistance via restricting the expansion of mesenchymal tumor subpopulations in breast cancer. Sci Rep. 2018,8(1):4013. doi: 10.1038/s41598-018-22340-7
    Read this paper
  • Fan LC, Jeng YM, Lu YT, et al. SPOCK1 Is a Novel Transforming Growth Factor-β-Induced Myoepithelial Marker That Enhances Invasion and Correlates with Poor Prognosis in Breast Cancer. PLoS One. 2016,11(9):e0162933. doi: 10.1371/journal.pone.0162933
    Read this paper