PERK-IN-4

MedChem Express

PERK-IN-4 [1337531-89-1]

10

1337531-89-1

Research Use Only

98.30

C24H19F4N5O

469.43

PERK-IN-4 is a potent and selective PERK (protein kinase R (PKR)-like endoplasmic reticulum kinase) inhibitor with an IC 50 of 0.3 nM. PERK is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states [1] .

NC1=C(C2=NC=N1)C(C3=CC=C4C(CCN4C(CC5=CC(C(F)(F)F)=CC(F)=C5)=O)=C3)=CN2C

-20°C,2°C to 8°C

12352200