Bio-Connect

Pexmetinib (ARRY-614)

M5873
AbMole BioScience
CAS Number945614-12-0
Product group Chemicals
Estimated Purity>98%
Molecular Weight556.63
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Pexmetinib (ARRY-614)
  • Delivery Days Customer
    9
  • CAS Number
    945614-12-0
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C31H33FN6O3
  • Molecular Weight
    556.63
  • Scientific Description
    Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
  • SMILES
    CC1=CC=C(C=C1)[N]2N=C(C=C2NC(=O)NCC3=C(OC4=CC5=C(C=C4)[N](CCO)N=C5)C=CC(=C3)F)C(C)(C)C
  • UNSPSC
    12352200