PF-00446687 (free base) [862281-92-3]

MedChem Express

PF-00446687 (free base) [862281-92-3]

10

862281-92-3

Research Use Only

99.78

C28H36F2N2O2

470.59

PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 +/- 1 nM[1]. Pf-446687 is brain penetrant[2].

O=C(N(C[C@@H]1C)C[C@H]([C@@]1(O)C2=CC=CC=C2)C)[C@H](C3)[C@H](C(C=CC(F)=C4)=C4F)CN3C(C)(C)C

-20°C,2°C to 8°C

12352200