PF-02413873

MedChem Express

PF-02413873 [936345-35-6]

10

936345-35-6

Research Use Only

99.29

C18H21N3O3S

359.44

PF-02413873 (PF-2413873) is a potent selective, fully competitive and orally active nonsteroidal progesterone receptor (PR) antagonist, with a Ki of 2.6 nM. PF-02413873 can block progesterone binding and PR nuclear translocation, and inhibit endometrial growth in vivo[1][2].

N#CC1=C(C)C=C(OC2=C(C)N(CS(=O)(C)=O)N=C2C3CC3)C=C1C

-20°C,2°C to 8°C

12352200