PF-03463275

Biorbyt

PF-03463275

10

1173239-39-8

Research Use Only

99.86%

C19H22ClFN4O

376.86

PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS permeability and may be used to ameliorate cognitive deficits associated with schizophrenia.

[H][C@@]12CN(C)C[C@]1([H])[C@H]2CN(Cc1ccc(F)c(Cl)c1)C(=O)c1cn(C)cn1

-20°C

12352200