PF-03654746 [935840-31-6]

MedChem Express

PF-03654746 [935840-31-6]

10

935840-31-6

Research Use Only

C18H24F2N2O

322.39

PF-03654746 is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 reduces allergen-induced nasal symptoms, might be a novel therapeutic strategy to further explore allergic rhinitis[1]. PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimers disease (AD)[2].

O=C([C@H]1C[C@@](C2=CC=C(CN3CCCC3)C(F)=C2)(F)C1)NCC

12352200