![PF-04418948 [1078166-57-0] PF-04418948 [1078166-57-0]](https://www.targetmol.com/group3/M00/35/64/CgoaEGayHemETN-tAAAAAA1UGAM039.png)
PF-04418948 [1078166-57-0]
T3306
CAS Number1078166-57-0
Product group Chemicals
Estimated Purity99.45%
Molecular Weight409.41
Overview
- SupplierTargetMol Chemicals
- Product NamePF-04418948 [1078166-57-0]
- Delivery Days Customer4
- CAS Number1078166-57-0
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NamePF-04418948
- Estimated Purity99.45%
- Molecular FormulaC23H20FNO5
- Molecular Weight409.41
- Scientific DescriptionPF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a diverse panel of GPCRs and ion channels at a concentration of 10 microM. Inhibits PGE2-induced increases in intracellular cAMP; reverses PGE2-invoked relaxation of mouse trachea (IC50 = 2.7 nM).
- Shelf life instruction3 years
- SMILESCOc1ccc2cc(OCC3(CN(C3)C(=O)c3ccc(F)cc3)C(O)=O)ccc2c1
- Storage Instruction-20°C
- UNSPSC12352200