PF-04447943 [1082744-20-4]

TargetMol Chemicals

PF-04447943 [1082744-20-4]

9

1082744-20-4

Chemical

Research Use Only

PF-04447943

99.11%

C20H25N7O2

395.46

PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting oxidative stress, inflammation, and modulating T-cell polarization, and may be useful for research on sickle cell anemia.

3 years

C[C@@H]1CN(Cc2ncccn2)C[C@H]1c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1

-20°C

12352200